Kuoth Wiel was born to a Sudanese mother and father in Itang, Ethiopia. Due to the war in Sudan her parents managed to escape to Ethiopia. In 1993 she lost her father to the war and in 1998 immigrated to the United States with her mother and siblings. She attended Trinity Lutheran School in Faribault, Minnesota and graduated from Faribault High School.
In high school she volunteered for the Big Brothers and Big Sisters Program of Southern Minnesota. She also excelled in Athletics and often translated for the Sudanese community in Faribault, Minnesota. She was involved in church youth groups and advocating for the Sudanese refugee community. She attended Augsburg College in Minneapolis and worked as a fashion model part time. During her years at Augsburg College she became an active member of the Trio Program and the Pan African Student Union (PASU). In Minneapolis she was active in community service volunteering her time at the East African Women Center. At the Center she looked after children whose mothers were from various parts of East Africa and was involved in teaching the English language to the women who came to the center. During her senior year she worked as an intern at Hope Village, a Psychiatric and Counseling office, providing psychological services to immigrants from East Africa. For her senior seminar, she conducted extensive research on mental Illness and trauma with a focus on Sudanese refugees.
During her senior year Kuoth landed her first movie role in The Good Lie starring Reese Witherspoon, which depicts the history of the Lost Boys and Girls of Sudan. She starred as a lost girl called Abital Deng. While filming she graduated from Augsburg College with a Bachelor of Arts Degree in Social Psychology in May of 2013. She continues to be active in the South Sudanese community working with youth to get them involved in peaceful advocacy. Kuoth is involved in a South Sudan women's group called South Sudan Women United as an advocate for the rights of women and children in South Sudan.
Kuoth is currently pursuing her career in acting in Los Angeles, California and using her voice to advocate for peace in South Sudan.